Metabolic
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"As the understanding of equine metabolic diseases advances, so too must the management strategies implemented to care for horses at risk of developing or diagnosed with these problems. For some of these syndromes, dietary changes can completely ameliorate clinical signs. For other syndromes, dietary modifications decrease the likelihood of serious complications.
Some metabolic diseases such as Pituitary Pars Intermedia Dysfunction (PPID or Equine Cushing’s disease) and Equine Metabolic Syndrome (EMS) involve problems with the endocrine system. Others, such as those that result in tying-up, are related to inherited genetic defects and abnormal muscle metabolism. Laminitis, however, may occur from a variety of causes and horses with some metabolic syndromes are at higher risk for this condition." - Kentucky Equine Research